Pharmaceutical manufacturing typically take place in regulated and stringent environments 
such as cleanrooms. Cleanrooms are basically controlled spaces that are measured by their 
particle and microbial counts according to the cleanroom ISO standards and regulated under 
GMP guidelines.

Requirements, ISO ratings and cleanliness standards for cleanrooms generally differ among 
the industries. More stringent sanitation standards are normally required of cleanrooms 
with higher ISO and cleanliness ratings in order to keep the level of particle 
contaminants out.

To meet these stringent cleanliness requirements, cleaning techniques as well as their 
type and application of cleaning agents such as disinfectants must also be well-managed. 
Disinfectants must be able to destroy and inhibit bacteria and other micro-organisms. 
On top of it, sensitive and delicate components used in cleanroom manufacturing can be 
costly and must be protected against any abrasion or from dirt during cleaning.  
All these can attribute to a challenging and time-consuming process for cleaning 
and maintenance.

Dry ice blasting, on the other hand, is an ideal solution for cleanroom maintenance 
because of its ability to carry out cleaning in controlled environments. Dry ice 
cleaning basically utilises frozen CO2 pellets or shaved ice that sublimate upon 
impact to lift contaminants off surfaces. Dry ice blasting can:

•    Clean without need of chemicals and does not leave any by-products. Unlike 
      chemicals or disinfectants where residue might linger on surfaces after 
      cleaning, dry ice cleaning uses only dry ice that sublimates, leaving 
      zero secondary waste.

•    Clean without causing abrasion and damage to sensitive and delicate components; 
      thereby, preserving their quality and condition.

•    Clean safely with no harm to electrical wiring and insulation because 
      no water is being used due to the lack of liquefaction.

•    Clean in situ quickly and thoroughly, reducing the downtime and 
      improving productivity.

Dry ice blasting is a non-toxic and eco-friendly cleaning solution that can effectively 
decontaminate a wide variety of surfaces, while protecting their integrity and quality.